Ca-induced Ca release in malignant hyperthermia susceptible pig
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منابع مشابه
Stretch-induced Ca release via an IP3-insensitive Ca channel
Mohanty, Madhumita Jena, and Xingli Li. Stretchinduced Ca2 release via an IP3-insensitive Ca2 channel. Am J Physiol Cell Physiol 283: C456–C462, 2002. First published May 15, 2002; 10.1152/ajpcell.00057.2002.—Various mechanical stimuli increase the intracellular Ca2 concentration ([Ca2 ]i) in vascular smooth muscle cells (VSMC). A part of the increase in [Ca2 ]i is due to the release of Ca2 fro...
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THIS MONOLOG is part of an APS series on major findings that have shaped many of our present concepts regarding what we currently understand as physiology. The process of Ca-induced Ca release was a topic of much discussion and debate when first introduced. The seminal manuscript on this topic is often considered that of Alexandre Fabiato, “Calcium-induced release of calcium from the cardiac sa...
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We investigated the dependence of nicotinate-adenine dinucleotide phosphate (NAADP)-induced Ca2+ release from intracellular stores of sea urchin egg homogenates, upon extravesicular Ca2+. In contrast to the Ca2+ release induced inositol 1',4',5'-triphosphate (IP3) or cyclic ADP-ribose (cADPR), the Ca2+ release induced by NAADP was completely independent of the free extravesicular Ca2+ over a wi...
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Fellner SK, Arendshorst WJ. Voltage-gated Ca entry and ryanodine receptor Ca -induced Ca release in preglomerular arterioles. Am J Physiol Renal Physiol 292: F1568–F1572, 2007. First published December 26, 2006; doi:10.1152/ajprenal.00459.2006.—We have previously shown that in afferent arterioles, angiotensin II (ANG II) involves activation of the inositol trisphosphate receptor (IP3R), activat...
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Despite extensive research, the mechanisms responsible for the graded nature and early termination of Ca -induced Ca release (CICR) from the sarcoplasmic reticulum (SR) in cardiac muscle remain poorly understood. Suggested mechanisms include cytosolic Ca -dependent inactivation/adaptation and luminal Ca -dependent deactivtion of the SR Ca release channels/ryanodine receptors (RyRs). To explore ...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1987
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)58455-4